Last edited by Munris
Sunday, August 2, 2020 | History

2 edition of Studies on phencyclidine (PCP) and 1-piperidi-nocyclohexanecarbonitrile(PCC) found in the catalog.

Studies on phencyclidine (PCP) and 1-piperidi-nocyclohexanecarbonitrile(PCC)

James Russell Ballinger

Studies on phencyclidine (PCP) and 1-piperidi-nocyclohexanecarbonitrile(PCC)

by James Russell Ballinger

  • 344 Want to read
  • 4 Currently reading

Published .
Written in English


The Physical Object
Pagination1 v., 174 leaves
Number of Pages174
ID Numbers
Open LibraryOL18942347M

  Developed by faculty at leading medical universities, these patient case study materials encourage sound opioid prescribing practices and discussion, problem-based learning, and skills-based practice related to the identification and care . @article{osti_, title = {Identification and quantification of phencyclidine pyrolysis products formed during smoking}, author = {Lue, L P and Scimeca, J A and Thomas, B F and Martin, B R}, abstractNote = {As a result of frequent phencyclidine (PCP) abuse, pyrolysis studies were conducted to further investigate its fate during smoking.

Print book: National government publication: EnglishView all editions and formats: Rating: (not yet rated) 0 with reviews - Be the first. Subjects: Phencyclidine -- Case studies. Phencyclidine abuse -- United States -- Case studies. Phencyclidine Abuse. View all subjects; More like this: User lists; Similar Items. T1 - Phencyclidine intoxication. T2 - A literature review. AU - Sioris, L. J. AU - Krenzelok, E. P. PY - /12/1. Y1 - /12/1. N2 - The history, symptoms, diagnosis and treatment of phencyclidine hydrochloride (PCP) intoxication and the pharmacology of PCP are reviewed.

Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. Introduction. Phencyclidine (PCP; 1-(1-phenylcyclohexyl) piperidine) was first synthesized in and originally developed in the mids as a general anesthetic agent for humans with its major advantage being induction of analgesia and amnesia without respiratory depression (1).It binds to the N-methyl-D-aspartate receptor and increases the catecholamine activity in the .


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Studies on phencyclidine (PCP) and 1-piperidi-nocyclohexanecarbonitrile(PCC) by James Russell Ballinger Download PDF EPUB FB2

- Phencyclidine Revisited - Structure Activity Relationships of Phencyclidine Derivatives - Synthesis, Conformation, and Physical Properties - Receptor Sites for Phencyclclidine in Mammalian Brain and Peripheral Organs - Identification and Characterization of [3H] Phencyclidine Binding to Specific Brain Receptor Sites - Integrated Studies5/5(1).

Angel Dust: An Ethnographic Study of Phencyclidine Users [Feldman, Harvey W., Agar, Michael, Beschner, George M.] on *FREE* shipping on qualifying offers. Angel Dust: An Ethnographic Study of Phencyclidine UsersAuthor: Michael Agar. Phencyclidine (PCP) Interpretation. The clearance half-life of PCP averages 15 hours.

The presence of PCP > LOQ indicates exposure to PCP within 2 to 8 days prior to specimen collection. Confirmation Tests: Phencyclidine (PCP). Abstract The serendipitous discovery of phencyclidine (PCP) in sets the stage for significant research efforts that resulted in a plethora of analogs and derivatives designed to explore the biological effects of this by: Fauman MA, Fauman BJ ().

The psychiatric aspects of chronic phencyclidine (PCP) use: A study of phencyclidine users. In Phencyclidine (PCP) Abuse: An Appraisal, Petersen RC, Stillman, RC, eds., pp.

– Rockville, MD: National Institute on Drug Abuse. Google ScholarCited by: 1. Phencyclidine, a substance of abuse also know as 'angel dust', can cause physical and psychological distresses, such as coma, seizures, convulsions, respiratory depression, and cardiac problems. Definition (MSH) A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans.

Pradhan SN. Studies on Studies on phencyclidine book effects of PCP have been conducted in volunteers in the ArmyLaboratories and elsewhere and in illicit users. The present review hassummarized the observations of many investigators which showed that the acuteeffects of PCP following several routes of administration were shown to bedose-related.

High doses of PCP produce disturbing. Fry: A Study of Adolescents' Use of Embalming Fluid with Marijuana and Tobacco - TCADA, Feb Phencyclidine (PCP) Abuse: An Appraisal - NIDA Research Monogr Aug CHEMISTRY & PHARMACOLOGY #.

Phencyclidine or phenylcyclohexyl piperidine (PCP), also known as angel dust among other names, is a drug used for its mind-altering effects. PCP may cause hallucinations, distorted perceptions of sounds, and violent behavior. As a recreational drug, it is typically smoked, but may be taken by mouth, snorted, or injected.

It may also be mixed with cannabis or tobacco. Phencyclidine is known chemically as 1-(1-phencyclohexyl) piperidine. It is considered a hallucinogen and a dissociative drug. Physically, phencyclidine is a white crystal-like powder, dissolves in water or alcohol, and has a bitter medicinal taste.

Quantitation of Phencyclidine, Its Metabolites, and Derivatives by Gas Chromatography with Nitrogen-Phosphorus Detection: Application for In Vivo and In Vitro Biotransformation Studies. A follow-up study of 57 phencyclidine exposed children showed that 65% experienced neonatal narcotic withdrawal syndrome.

At 1 year of age there was no difference in a behavioral assessment compared to a control group (Wachsman ). Phencyclidine is an illegal, hallucinogenic drug that was initially used as an anesthetic agent in the s and early s, but was then withdrawn in because of dissociative hallucinogenic effects that were often disturbing and sometimes severe and prolonged.

Phencyclidine (PCP) is a synthetic compound derived from piperidine with anesthetic and hallucinogenic properties. PCP use as a recreational drug is resurging. The Substance Abuse and Mental Health Services Administration repor emergency department (ED) visits related to PCP use. Immediately download the Phencyclidine summary, chapter-by-chapter analysis, book notes, essays, quotes, character descriptions, lesson plans, and more - everything you need for studying or teaching Phencyclidine.

AU - Cone, E. PY - Y1 - N2 - A series of phencyclidine (PCP) related analogs, carbonitrile synthetic precursors and two monohydroxylated metabolites were compared pharmacologically in mice for their ability to produce ataxia using the rotarod method and toxicologically for their acute 4-hr lethality.

Vrio analysis for Phencyclidine case study identified the four main attributes which helps the organization to gain a competitive advantages. The author of this theory suggests that firm must be valuable, rare, imperfectly imitable and perfectly non sustainable.

A binding study assessed PCP at 56 sites including neurotransmitter receptors and transporters and found that PCP had K i values of >10, nM at all sites except the dizocilpine (MK) site of the NMDA receptor (K i = 59 nM), the σ 2 receptor (PC12) (K i = nM), and the serotonin transporter (K i = 2, nM).

Phencyclidine, more commonly referred to as PCP, is a popular hallucinogen. Originally developed as an anesthetic in the s, it was discontinued and replaced by Ketamine, (another anesthetic that is similar in structure to PCP) after its.

Subchronic administration of phencyclidine (PCP), an NMDAR antagonist, produces a variety of cognitive impairments in rodents. Of these, novel object recognition, a type of declarative memory, has been widely used to study the pathophysiology resulting from PCP treatment.

Abstract. Phencyclidine (PCP) is a drug of abuse which may produce, in some users, a persistent schizophreniform psychosis. The possibility that long term effects of PCP are mediated by metabolic activation of the parent compound to reactive species is consistent with the demonstration of metabolism-dependent covalent binding of radiolabeled PCP in vivo and in.

(). Phencyclidine (PCP): A Review and Perspectives. CRC Critical Reviews in Toxicology: Vol. 10, No. 2, pp. Street names for PCP include angel dust, embalming fluid, hog, killer weed, love boat, ozone, peace pill, rocket fuel, super grass, wack. PCP's Effects on Your Brain. PCP is a mind-altering drug.

This means it acts on your brain (central nervous system) and changes your mood, behavior, and the way you relate to the world around you. Scientists.